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publicationDate 2019-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10412939-B2
titleOfInvention Rodent model of prostate cancer
abstract This disclosure provides a rodent model of prostate cancer. The rodents disclosed herein comprise a transgene that provides prostate-specific expression of an oncogenic protein (e.g, an SV40 tumor antigen) under the control of 5′ and 3′ regulatory regions of a mouse probasin gene. The rodents develop progressive forms of prostate tumor that resemble the development of human prostate cancer.
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