| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e41651508566f0385833e1ba14a21ffd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2194526090510d3d3b4357f0fb3bcf05 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C229-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-543
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-88
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2017-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_255ae6cec4b3000d2f41bc176e12bf25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7468eccf2917511ebb5e1905f7d8149e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae58f815dbc67582d1df24f33aeced7a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2aadb0051e75e65a27d2c8ec07377ed |
| publicationDate |
2019-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-10406237-B2 |
| titleOfInvention |
Amine-containing transfection reagents and methods for making and using same |
| abstract |
There are provided for herein novel amine-containing transfection compounds and methods for making and using same. The compounds are generally obtained by reacting a primary amine with an unsaturated compound. Transfection complexes made using the amine-containing transfection compounds in combination with additional compounds to encapsulate biologically active agents such as nucleic acids are also provided for herein. Methods of using the transfection complexes for the in vivo or in vitro delivery of biologically active agents are also described. The transfection complexes of the present invention are highly potent, thereby allowing effective modulation of a biological activity at relatively low doses compared to analogous transfection compounds known in the art. |
| priorityDate |
2010-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |