http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10392354-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9cc2d8f832624f015bd24bec47ef697 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-22 |
| filingDate | 2018-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3210f156c4103f50334c7d53d8d1c791 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_437436456e0e33be4bde65de61196d78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b129c0c261858570c976f4c88172c1d |
| publicationDate | 2019-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-10392354-B2 |
| titleOfInvention | Highly selective anti-cancer agents targeting non-small cell lung cancer and other forms of cancer |
| abstract | Described herein are analogs of 2-methyl-3-(2-ethynylthiazol-4-yl)cyclopent-2-enol and the corresponding ketone 3-(2-ethynylthiazol-4-yl)-2-methylcyclopent-2-enone, the analogs having terminal alkyne groups at the 2-position of the thiazole ring. These drug-like molecules, referred to as CETZOLE compounds, are useful to treat non-small cell lung cancer and other forms of cancer. Methods of making and using the compounds, methods of treating various diseases, pharmaceutical compositions, and kits are also disclosed. |
| priorityDate | 2013-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 186.