Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_27fade90728c3023697f458de968333c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
filingDate |
2016-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2019-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c54ed187beea03786c0a7753205650a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f7fe8dc8ef62f628681cdcfd73232ea http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf18a31b8f1b4cf79151d907a6613df5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f41a71ddf2edc0a0e48f0dfe65c05c96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04930fdd8c7ffe851b71818f7779b2e2 |
publicationDate |
2019-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10377757-B2 |
titleOfInvention |
Crystal form of JAK inhibitor and preparation method thereof |
abstract |
The present disclosure relates to novel crystalline forms of JAK inhibitors and the preparation method thereof. The novel crystalline forms in the present disclosure can be used for the treatment of autoimmune diseases, particularly for the treatment of rheumatoid arthritis. The novel crystalline forms in the present disclosure have good stability and remarkable purification effect in process, moreover, its solubility and hygroscopicity meet the requirements for medical use. The preparation method of novel crystalline forms is simple, low cost, and has an important value for future optimization and development of the drug. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020072870-A1 |
priorityDate |
2015-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |