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filingDate 2016-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13f10cc1130814c395f5af27f222f02b
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publicationDate 2019-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10376611-B2
titleOfInvention Multilayered bone graft and method of making same
abstract A synthetic bone graft is described which is adapted to be received within a bone defect and which is structurally load-bearing. The bone graft comprises an entirely synthetic graft body corresponding in shape and size to the bone defect. The graft body is composed of a plurality of superimposed multilayered structures, each of the multilayered structures having a biopolymer layer joined to a biomineral layer to define an interface therebetween. The biomineral layer has a stiffness that is greater than that of the biopolymer layer, and the biopolymer layer has a toughness that is less than that of the biomineral layer.
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