http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10352947-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_adff709a8d25eaa0d3871ff46ff250eb |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-325 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-50 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-567 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2013-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13fa488b51e28f123203e8be8e687038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2324b1b71d55bd49ff08b361c321d54f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ebc3bb1a8ae92666a53ec88f223928f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ecf5874b7b757deef6ee5b1e36af957 |
publicationDate | 2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-10352947-B2 |
titleOfInvention | Use of markers in the identification of cardiotoxic agents and in the diagnosis and monitoring of cardiomyopathy and cardiovascular disease |
abstract | The invention provides methods for the diagnosis and prognosis of cardiovascular disease, and for monitoring of the treatment of cardiovascular disease, including heart failure and cardiomyopathy. The invention further provides methods for identifying an agent for treating cardiomyopathy or heart failure, for identifying a cardiotoxic agent, and for identifying a rescue agent to reduce or prevent drug-induced toxicity, by using one or more biomarkers selelcted from the group consisting of CCDC47, HMOX1, PTX3, PAI1, IL27, IGFBP7, Emmprin, CFL2, EDIL3, NUCB1, PE D18:0-20:3/D18:1-20:2/D16:0-22:3; PE D18:0-22:5/D18:1-22:4; PE D16:1-22:6; PE P18:1-18:1/P18:0-18:2/P16:0-20:2; LPC 20:3; and PC-LI-183-D18:22-22:6, or any of the other biomarkers provided herein. The invention further provides kits for practicing the methods of the invention. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022124849-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11694765-B2 |
priorityDate | 2012-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 180.