Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33b011e77b33662b8bf1f2ff2de7b661 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6982089ec5a708f4b57f2cfa9d0330a1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-21 |
filingDate |
2017-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9e1b8dd508aad54d577a9690aad81fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96de878b5364137d2cfd771e7af5f849 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9732ef0e405f94aa6d00064ac1bd2f69 |
publicationDate |
2019-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10351605-B2 |
titleOfInvention |
Compositions and methods to prevent cancer by stabilizing p53 through non MDM2-mediated pathways |
abstract |
The present invention relates to compositions and methods comprising chemopreventive agents that may be cupredoxin(s) or variants, derivatives and structural equivalents of cupredoxins, and at least one other chemopreventive agent. Specifically, these compositions may comprise azurin from Pseudomonas aeruginosa, and/or the 50-77 residue region of azurin (p28). The compositions of the invention may be used to prevent or inhibit the development of premalignant lesions in mammalian cells, tissues and animals, and thus prevent cancer. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2020172581-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11046733-B2 |
priorityDate |
2004-10-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |