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filingDate 2016-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_35ff59357c3ebdfe7bdecf0a8ed8e828
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publicationDate 2019-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10323025-B2
titleOfInvention Crystallization procedure for obtaining canagliflozin hemihydrate crystals
abstract The present invention relates to an improved crystallization procedure to obtain canagliflozin hemihydrate crystals having a narrow particle size distribution by removing a small part of the crystalline suspension in the crystallization vessel from said vessel and subjecting said part to particle size reduction of the formed crystals followed by heating and reintroducting said part of the crystalline suspension again in the crystallization vessel which is kept within a specific temperature range.
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