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filingDate 2017-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_513bf453b67f565cfb0d1a9e06d3a082
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6678491859d1a991fac291e9d99a99a2
publicationDate 2019-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10308681-B2
titleOfInvention Pharmaceutical composition for the prevention and treatment of cardiovascular disease comprising the peptide having the ability to inhibit angiotensin-1 converting enzyme as an active ingredient
abstract The present invention relates to a peptide separated from the fraction of oyster enzyme hydrolysate displaying the ability of suppressing angiotensin converting enzyme (ACE) and a pharmaceutical composition for the prevention and treatment of cardiovascular disease comprising the said peptide as an active ingredient. Particularly, the peptide separated from the fraction of the oyster enzyme hydrolysate of the present invention significantly inhibits ACE activity, and thus brings blood pressure regulating effect and antihypertensive effect. Therefore, the fraction of the oyster enzyme hydrolysate of the invention or the peptide separated from the same can be effectively used as an active ingredient of a pharmaceutical composition for the prevention or treatment of cardiovascular disease.
priorityDate 2012-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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