http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10308672-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-572 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-572 |
| filingDate | 2017-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92a66e552455235a5f5e675ea029c447 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_363c667375b39423d803f61db932d49b |
| publicationDate | 2019-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-10308672-B2 |
| titleOfInvention | Method for producing monomer for single-stranded nucleic acid molecule |
| abstract | A compound represented by formula (3): n n n n n n n n n n n n or an enantiomer thereof can be obtained by comprising: n reacting a compound represented by formula (1): n n n n n n n n n n n n n n n n or an enantiomer thereof with 6-hydroxyhexanoic acid in a solvent in the presence of an additive such as 1-hydroxybenzotriazole and a condensing agent, and then mixing the resultant reaction mixture, water, and a base such as alkali metal hydroxide to produce a compound represented by formula (2): n n n n n n n n n n n n n n n n or an enantiomer thereof; and n reacting the compound represented by formula (2) or an enantiomer thereof with 2-cyanoethyl-N,N,N′,N′-tetraisopropylphosphorodiamidite in a solvent in the presence of a coupling activator. |
| priorityDate | 2016-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 292.