| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0669f10ac82c082c17a3bf9d4a941b96 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2207-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-035
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0368 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0278
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-495
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
| filingDate |
2015-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12ff51c69acc694fe0d59b4e23e68525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12539affd598d32689c430251e55307c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc0c61845c0663d14ef626b774fffa4b |
| publicationDate |
2019-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-10251378-B2 |
| titleOfInvention |
Transgenic mouse expressing kidney-specific human TGF-beta1, and biomarker for tissue fibrosis mouse model |
| abstract |
A transgenic mouse has a genome that includes the entire gene region of human transforming growth factor beta-1 (human TGFβ1) located downstream of a mouse Podocin promoter such that expression of the human TGFβ1 is controlled by the mouse Podocin promoter. The human TGFβ1 contains 7 exons and 6 introns, the human TGFβ1 is expressed in a kidney of the mouse as non-active TGFβ1 and becomes active TGFβ1 extracellularly, and the transgenic mouse spontaneously develops renal fibrosis. |
| priorityDate |
2014-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |