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filingDate 2015-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66c1b8fb63cf7a42205ae6d3fc7004df
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publicationDate 2019-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10246679-B2
titleOfInvention Method for producing pluripotent stem cell having improved chimera forming ability from primed pluripotent stem cell, and composition and combination therefor
abstract The present invention provides a method for putting a primed pluripotent stem cell in a less differentiated state, a method for producing a pluripotent stem cell having an improved chimera forming ability from a primed pluripotent stem cell, and a method for producing a chimeric animal by using the pluripotent stem cell obtained by any of these methods. The present invention also provides a composition containing a Wnt/β catenin signal inhibitor.
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