| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fcffd385b763387b8bc29b364cdd0f54 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2018-00613
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2018-00577
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2018-00446
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B2034-104
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-327 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B18-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B18-1206
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61B18-1477
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N13-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-327 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B34-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B18-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B18-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B18-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N13-00 |
| filingDate |
2013-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e707f9065e9974e5c51307c5d42a4e35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c23ff115aa5fe637114f39a7f04c016
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ef2856a02385cc7d36588e8be524ce8 |
| publicationDate |
2019-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-10245098-B2 |
| titleOfInvention |
Acute blood-brain barrier disruption using electrical energy based therapy |
| abstract |
A method is provided for ablating brain tissue of a living mammal comprising: placing first and second electrodes in a brain of the living mammal; applying a plurality of electrical pulses through the first and second placed electrodes which are predetermined to: cause irreversible electroporation (IRE) of brain tissue of the mammal within a target ablation zone; and cause a temporary disruption of a blood brain barrier (BBB) within a surrounding zone that surrounds the target ablation zone to allow material in a blood vessel to be transferred to the surrounding zone through the temporarily disrupted BBB. Such methods are useful for delivering large molecule material within a blood vessel of the brain across the BBB, where the large molecule is otherwise blocked by the BBB from passing through the blood vessel into the brain. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10828085-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10828086-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11382681-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10959772-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11406820-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11254926-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11453873-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10448989-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10470822-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10471254-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11638603-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11655466-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2023275804-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11607271-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11607537-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11311329-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11272979-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11707629-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3831442-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11723710-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11400283-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10694972-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10702326-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11786300-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11779395-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11737810-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10537379-B2 |
| priorityDate |
2008-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |