Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5ba2619e445cc332b3b00afeab15d422 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-91188 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-085 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57438 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-48 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-40 |
filingDate |
2014-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2019-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_823290fc8d4e5470ff09d8ba70156a73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17bda3595c223b61d1071f328b936565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f91399eb5bf27a6bdbfe0f9112993c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9eec213e3c799b295d915f73efa97e33 |
publicationDate |
2019-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10228373-B2 |
titleOfInvention |
Kit and method for diagnosis, prognosis or monitoring of liver disease through measurement of amount of AST |
abstract |
Disclosed are: a kit and a method for diagnosing or monitoring a liver disease, comprising a detection reagent for one or more markers of cytosolic aspartate aminotransferase (cAST) and mitochondrial aspartate aminotransferase (mAST) as biomarkers in a biological sample; and an antibody used for the detection. Compared to the conventional enzyme activity measurement method, the method according to the present application can more accurately measure diagnosis or prognosis of a liver disease with high sensitivity through measurement of the amount of mAST or cAST present in the biological sample, in particular, in a blood sample. |
priorityDate |
2013-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |