http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10227338-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2df2e1189fa8605916aa5ef7b6df8f95 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-497 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-21 |
| filingDate | 2016-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa164cc4ca27561e6477a6c3e99e2fe5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_322f4053388120705bca9b951b4afe0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7dacd3eea7c8fdc232146e21ac42900f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a9ab7867245e0ae2b3e7ab5be1dd988 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4379b37e1472bc042a0c735e7f08c3f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_731cc266ce6802f0d31ebd1f457d7e29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1086edf884a4a0038402c9a2b56a5502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fcee3069072e999973e5e3baefb4185 |
| publicationDate | 2019-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-10227338-B2 |
| titleOfInvention | Substituted benzenesulfonamides as sodium channel blockers |
| abstract | The invention relates to a compound represented by Chemical Formula 1, below, a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the compound or salt. The compound of the invention or pharmaceutically acceptable salts thereof can be used for the prevention or treatment of sodium channel blocker-related diseases. n n n n n n n n n n n n in Chemical Formula 1, n R 1 is hydrogen, C 1-4 alkyl, C 1-4 alkoxy, C 1-4 haloalkyl, C 1-4 haloalkoxy, halogen, or cyano, n R 2 and R 3 are each independently hydrogen, or halogen, n R 4 is C 5-10 heteroaryl containing one or two elements each independently selected from the group consisting of N, S and O, wherein the C 5-10 heteroaryl is unsubstituted or substituted with C 1-4 alkyl or halogen, n R 5 is —CH 2 CH 2 —N(R 7 )(R 8 ), or —CH 2 CH 2 CH 2 —N(R 7 )(R 8 ), R 6 is hydrogen, or C 1-4 alkyl; or R 5 and R 6 together form C 3-5 alkylene, (C 2-4 alkylene)-N(R 9 )—(C 2-4 alkylene), or (C 2-4 alkylene)-O—(C 2-4 alkylene), wherein the C 3-5 alkylene, or C 2-4 alkylene is each independently unsubstituted or substituted with one or two R 10 , n R 7 , R 8 , and R 9 are each independently hydrogen, or C 1-4 alkyl, n R 10 is C 1-4 alkyl, C 1-4 alkoxy, halogen, amino, NH(C 1-4 alkyl), N(C 1-4 alkyl) 2 , NHCO(C 1-4 alkyl), or pyrrolidinyl, n X 1 is C—R′, or N, wherein R′ is hydrogen, or halogen, n X 2 is CH, or N, and n X 3 is N—R″, wherein R″ is hydrogen, or C 1-4 alkyl. |
| priorityDate | 2015-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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