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filingDate 2016-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10213398-B2
titleOfInvention Methods for alleviating statin myopathy
abstract Disclosed herein are methods and compositions for alleviating side effects of statin administration, such as myopathic or myalgic side effects, short-term memory loss, abnormal liver function, glucose intolerance, hyperglycemia, increased risk for diabetes, or cumulative trauma disorder, comprising administration of β-hydroxy β-methylbutyrate (HMB) to an individual taking a statin. Also disclosed are methods and compositions for alleviating acute rhabdomyolysis comprising administration of HMB. The disclosure further provides uses of HMB in combination with a statin to alleviate side effects of statin administration.
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