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filingDate 2017-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc9b21ec6e3fa56c5d1a64404ab2ec92
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publicationDate 2019-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10188630-B2
titleOfInvention Methods for identifying and using inhibitors of casein kinase 1 epsilon isoform for inhibiting the growth and/or proliferation of MYC-driven tumor cells
abstract In one aspect, the invention provides a method for inhibiting the growth and/or proliferation of a myc-driven tumor cell comprising the step of contacting the tumor cells with a CSNK1ε inhibitor. In another aspect, the invention provides a method of treating a subject suffering from a tumor comprising myc-driven tumor cells, comprising administering to the subject an amount of a composition comprising a CSNK1ε inhibitor effective to inhibit the growth and/or proliferation of the tumor cells.
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