http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10183925-B2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a6cdbd27eae70f335090155ab882f6b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7df267c0e21d6b0ad2a3490807c38477 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D407-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 |
filingDate | 2016-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8b05ca5c04192bd51ed07e96637feb1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9bc17b03096f09410c5a3319c26e4858 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_369e260d95404994b495901f51e23958 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc70e211f3319db11b80d153bb2ed3cd |
publicationDate | 2019-01-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-10183925-B2 |
titleOfInvention | Substituted naphtho[2,3-b]furans as water-soluble prodrugs for preventing and/or treating cancer |
abstract | The present invention provides compounds represented by formula (1A), or pharmaceutically acceptable salts. Compounds represented by formula (1A), or pharmaceutically acceptable salts thereof, wherein A 1 and A 2 are identical or different, and each independently —C(═O) B, —C(═O)CR 3A R 3B B, —CO 2 B, —C(═S)OB, —CONR 3C B, —C(═S)NR 3C B, a hydrogen atom, or the like, wherein A 1 and A 2 are not both hydrogen atoms, wherein B is an optionally substituted 3- to 12-membered monocyclic or polycyclic heterocyclic group, an optionally substituted 3- to 12-membered cyclic amino group, or a group represented by the following formula (B), wherein the 3- to 12-membered monocyclic or polycyclic heterocyclic group and the 3- to 12-membered cyclic amino group have at least one or more secondary nitrogen atoms in the ring; R 1 is a hydrogen atom or the like; R 2A , R 2B , R 2C , and R 2D are identical or different, and each independently a hydrogen atom or the like; and R 8 is alkyl. n nwherein * denotes a bonding position. |
priorityDate | 2015-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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