Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_89e7e627832cafed0a5ffdf86275b89f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b3e6d8f05d9475eab2cebb5c85f9f80 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2016-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2019-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be13b155bd7e9a8d2e8b6ef23c102936 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8be82b40f0dab81f3fdb95a0986bd923 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cefd7973adfce754257319068c6f8cd9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34a722f109f39782c90255724f6cfcf6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa4ad790ddc9c2a926afccb9d9a4b9a0 |
publicationDate |
2019-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10166203-B2 |
titleOfInvention |
Pharmaceutical composition for treating cancer including 2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol as active ingredient |
abstract |
The present disclosure relates to an anticancer use of a novel compound, i.e., 2-methoxy-4-(3-(4-methoxyphenyl)propyl-1-en-1-yl)phenol. The compound of the present disclosure effectively inhibits the growth of cancer cells and tumors in vitro and in a xenograft animal model. The compound of the present disclosure illustrates an anticancer activity by inhibiting a DNA binding activity of transcription factor STAT 3 in cancer cells, inducing apoptosis of cancer cells, and reducing the expression of a cell cycle regulatory protein. The compound of the present disclosure can be developed as an active ingredient of a strong anticancer drug. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2019175521-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10918609-B2 |
priorityDate |
2015-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |