Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_520453d29d5107705d2dcaefbf0625cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f6d7f8f441b4c89b8006ff4e48d711e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07c3416818d6a9e023536505526b0f1c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe09ff39e35d6bf3a1571f733e7a895f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_df4a9f4fdc3912d8f545402dfd0dac05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b92cfb8d271c5acc606b6656d2fa929 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6858 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6858 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 |
filingDate |
2009-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98cd919b772887c3d229c3c37b1f60ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8abae43abb5348fdf4cdf7d906e3ea49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1ba806646a0a6cdb1bab81e8a674995 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a51eb1205667a97d52a6d55ebf59598a |
publicationDate |
2018-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10150990-B2 |
titleOfInvention |
Ribonucleotide tag nucleic acid detection |
abstract |
The present application provides polynucleotides comprising 5′-tails with sequence segments useful for the detection of target nucleic acid sequences, and methods for their use in detecting target nucleic acids. The polynucleotides are used to amplify a subsequence of a target nucleic acid in the presence of one or more ribonucleotides. The ribonucleotides are incorporated into amplification products at regular intervals complementary to the 5′-tail sequence segments. Cleavage of amplification products at the bond immediately 3′ to incorporated ribonucleotides produces detectably distinct fragments indicative of the presence or absence of a target nucleic acid. |
priorityDate |
2008-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |