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grantDate 2018-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2018-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10121645-B2
titleOfInvention Sheathless interface for capillary electrophoresis/electrospray ionization-mass spectrometry
abstract Provided herein are capillaries for use in an electrophoretic separations. The capillaries can comprise an elongated tubular wall defining a path for fluid flow from an inlet to a tapered outlet; and a decoupler junction positioned within the elongated tubular wall upstream of the tapered outlet. The decoupler junction can comprise a plurality of microchannels penetrating through the elongated tubular wall and an ion-permeable polymer coating the plurality of microchannels. Also provided are sheathless interfaces for coupling capillary electrophoresis (CE) with mass spectrometry that employ these capillaries.
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