Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_98616e7e427eaa2fede2d80f145f98cc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d744f039a6435a3273d9f8319481d83 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4974763aebe002c0c8afe4455c0ee6c8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L2203-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-075 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-222 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0656 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0012 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L67-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L67-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38 |
filingDate |
2017-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c3125d886fa9ad845be7d8aedb0487a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_931b4c1959bf731e306444180af172bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a93a2f6714944cbb54b43818d1e7438 |
publicationDate |
2018-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10117967-B2 |
titleOfInvention |
Scaffold for skin tissue engineering and a method of synthesizing thereof |
abstract |
The embodiments herein disclose a method of fabricating composite scaffolds for skin tissue regeneration. The methacrylated hyaluronic acid (HAMA) and methacrylated gelatin (GelMA) are synthesized. The poly (glycerol sebacate)-poly(ε-caprolactone) (PGS-PCL) microfibrous scaffolds are synthesized. The hydrogel is synthesized. The composite scaffold comprising hydrogel and poly (glycerol sebacate)-poly(ε-caprolactone) (PGS-PCL) microfibrous scaffolds is fabricated. A plurality of physico-chemical characteristics of the composite scaffold comprising hydrogel and poly (glycerol sebacate)-poly(ε-caprolactone) (PGS-PCL) microfibrous scaffolds are analysed. The physico-chemical characteristics comprises mechanical properties, swelling ratio and enzymatic degradation and scanning electron microscope imaging. The fibroblast cells are encapsulated within the composite scaffold comprising hydrogel and poly (glycerol sebacate)-poly(ε-caprolactone) (PGS-PCL) microfibrous scaffolds and hydrogels. The fibroblast cells are seeded on composite scaffold and PGS-PCL scaffold. The fibroblast cell viability, fibroblast cell attachment, fibroblast cell spreading, fibroblast cell proliferation and fibroblast cell metabolism are analysed in composite scaffolds, PGS-PCL scaffolds and hydrogels. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109758608-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111214702-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109758608-A |
priorityDate |
2017-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |