Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_589313a9cb1f5c4276e4bd30a89880e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0483f831051c79181eda0b93bc1b3589 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf1c6809d38f7bc0eb0c8c9e5eacef34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e3a37bacca144d78b49a86fe89235e36 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-2982 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G83-004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-3348 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-329 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L71-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L71-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-329 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G83-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-334 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-60 |
filingDate |
2012-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_989724ef4bf50676a3a708ba6ff9cea7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d4648f142d5aa70e09aa0022670334b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_049847495b951ef1bf5d047c69575eec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e807c26e4c9b5fd39ebda03d0c2f2dcf |
publicationDate |
2018-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10106650-B2 |
titleOfInvention |
Reversibly crosslinked micelle systems |
abstract |
The present invention provides amphiphilic telodendrimers that aggregate to form nanocarriers characterized by a hydrophobic core and a hydrophilic exterior. The nanocarrier core may include amphiphilic functionality such as cholic acid or cholic acid derivatives, and the exterior may include branched or linear poly(ethylene glycol) segments. Nanocarrier cargo such as hydrophobic drugs and other materials may be sequester in the core via non-covalent means or may be covalently bound to the telodendrimer building blocks. Telodendrimer structure may be tailored to alter loading properties, interactions with materials such as biological membranes, and other characteristics. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11369688-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11219692-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11318097-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11179335-B1 |
priorityDate |
2011-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |