http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10106550-B2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c806892c768c1ade2e5f1bdcf14e66f7 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-16 |
filingDate | 2016-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03a426b008b05818aa13d24cace1d9b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da0cb8e89476de1c680c2d2a6597b65e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d77ab4bb9c318f5b72eeabf10d340ac6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e507706e2608279c9f5ea11ced79cd4 |
publicationDate | 2018-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | US-10106550-B2 |
titleOfInvention | Aza-phenalene-3-ketone derivative, preparation method thereof, and its application as PARP inhibitor |
abstract | Disclosed are an aza-phenalene-3-ketone derivative, a preparation method thereof and its application as a PARP inhibitor. The aza-phenalene-3-ketone derivative has the following structure: n nwherein R is hydrogen, methyl, ethyl, isopropyl, benzyl or 3-methyl-3-butenyl. The aza-phenalene-3-ketone derivative has very high activity for inhibiting PARP, thereby providing a good basis for new drug research of developing a nitrogen-doped phenalene-3-ketone compound as PARP inhibitor to treat cancer. |
priorityDate | 2015-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 145.