Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1763f7f78d01cad638210d060676591a |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-10011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-108 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-70596 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8778 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-90 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-877 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705 |
filingDate |
2016-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_181a4ccce7fab4eaf734d10aa88dacb6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0875cbcb6175280857382d9865efbaff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76fd5eb4f69e5c88f9e3c1cb417d77a7 |
publicationDate |
2018-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10091975-B2 |
titleOfInvention |
Pathogen-resistant animals having modified CD163 genes |
abstract |
Non-human animals and offspring thereof comprising at least one modified chromosomal sequence in a gene encoding a CD163 protein are provided. Animal cells that contain such modified chromosomal sequences are also provided. The animals and cells have increased resistance to pathogens, including porcine reproductive and respiratory syndrome virus (PRRSV). The animals and offspring have chromosomal modifications of a CD163 gene. The invention further relates to methods of breeding to create pathogen-resistant animals and populations of animals made using such methods. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11160260-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2021112790-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11019809-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11535850-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022081868-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11208659-B2 |
priorityDate |
2015-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |