Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fa59095cb78a37d0da1cb16378010aa1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae0f4a377a23a1801e91e3440f276c09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_255ea743d5f234e70fb6a537572bcaa2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96140f84dae7761ceb577b47b40fef70 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2810-40 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-645 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-48315 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
filingDate |
2015-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e443947343492851829affdcc47308d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f9bc6786d39ebc31e1ad743d3fe3cef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30473f1a2f41539e96ac5ca4dd070831 |
publicationDate |
2018-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10058620-B2 |
titleOfInvention |
Dextran-peptide hybrid for efficient gene delivery |
abstract |
One or more embodiments of the present invention provide a novel composition for gene delivery are directed to a group of polysaccharide polymers, having one or more nucleic acid delivery side chains comprising cationic peptides. In some embodiments, these cationic peptides condense and physically bond to one or more nucleic acids to form a polysaccharide-nucleic acid complex that permits delivery to and transfection of the nucleic acid(s) into cells. In some embodiments, the polysaccharide polymers of the present invention may also have one or more zwitterionic side chains and/or reactive side chains. |
priorityDate |
2014-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |