http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10052369-B2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cea139ad438b9ce7d33159d45b154c6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_60165f3403b3b7f379f262fe11bd3909 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-552 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55566 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43527 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0003 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
| filingDate | 2016-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4649676337f6e2d03b5418164cd03a30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67fdf68af0d71f55ac61e5582ced7e21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90848f8786f696397017109401380d17 |
| publicationDate | 2018-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-10052369-B2 |
| titleOfInvention | Aquaporin 2 protects cattle from ticks and tick-borne parasites |
| abstract | A novel method of using an aquaporin protein from Rhipicephalus microplus (RmAQP2), fragments of RmAQP2, and/or the cDNA encoding RmAQP2 and/or the fragments are described. Immunogenic composition containing recombinant RmAQP2 and/or fragments of RmAQP2 are produced and administered to an ungulate which generates an immune response to RmAQP2. After feeding female ticks on the ungulate injected with RmAQP2 and/or fragments of RmAQP2, the female ticks have lower reproductive viability because of a reduced egg mass, reduced hatching percentage, and reduced survival of larvae. Thus, administering RmAQP2 and/or RmAQP2 fragments to an ungulate can reduce the incidence of R. microplus and also reduce the incidence of tick-borne pathogens in ungulates because of the lower number of R. microplus. |
| priorityDate | 2015-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 270.