Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_25202fe4a5c7293a0a5e07026316bf12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9bf8f65b7a046daeac45cf2717359c |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-803 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-803 |
filingDate |
2014-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3b736018606801e8350f1149a6cac0c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cda8fa31d76c52dff607e2e66c1548a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff4fad9fc26ef9143bb6f44b070ac604 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_871fca5631f9d36966d5ecd522afe38b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c4dbc59cfff32d2ff05002613ed582f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c222d4b0fcb362ea2cdcb23b0022f448 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_68f135c62560263a2b17a4c9d5357be7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_172d5eed17c13ac456a355d2775dbabb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_def4ad6a326339ff5845e7d49f0aa84e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1819af8353a95657baa49131955fa2ef |
publicationDate |
2018-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10035771-B2 |
titleOfInvention |
Mercaptonicotinic acid compound and preparation method and use thereof |
abstract |
The present invention discloses a class of mercaptonicotinic acid compound and preparation method and use thereof; the general structural formula of the compound is as shown in Formula I. Experiment demonstrates that the mercaptonicotinic acid compound could inhibit activity of botulinum toxin endopeptidase and tetanus toxin endopeptidase in vitro, which has a significant protective effect on botulinum toxin poisoning in mice, and can be used for preparing medicine intended to prevent and/or treat botulism, as well as to prevent botulinum toxin exposure and tetanus. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10981873-B2 |
priorityDate |
2013-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |