Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5dd388a5130b0bdede0fdfc6c2af6ed http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_238a0cbb4d846151b3a4844bad7f9879 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2001-302 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-0064 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6458 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H04N5-2256 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H04N9-797 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/H04N23-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-367 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-0076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G02B21-16 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02B21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02B21-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G02B21-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H04N5-225 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H04N9-797 |
filingDate |
2015-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cffb75116c71946a90bbe80806ac6d2 |
publicationDate |
2018-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-10001635-B2 |
titleOfInvention |
Rapid confocal microscopy to support surgical procedures |
abstract |
One embodiment of techniques for confocal microscopy includes illuminating a spot on a surface of a biological sample. A first emission intensity from the spot is detected in a first range of optical properties; and a second emission intensity in a second ranges A pixel that corresponds to the spot is colored using a linear combination of the first and second emission intensities. Sometimes, the pixel is colored to approximate a color produced by histology. In some embodiments, a surface of a sample is contacted with a solution of a nucleus dye. Then, a spot is illuminated with a laser beam of wavelength about 488 nanometers (nm). Fluorescence emission intensity is detected above about 500 nm. Sometimes, a certain illumination correction is applied. In some embodiments, a sample holder that compresses a sample is removable from a stage that is fixed with respect to a focal plane of the microscope. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-D831469-S |
priorityDate |
2008-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |