| abstract |
The invention relates to a solid formulation containing the following first and second parts: (1) the first part contains 2 - $ 6 - $ (3R) -3-amino-1-piperidinyl] -3,4-dihydro-3-methyl-2, 4-dioxo-1 (2H) -pyrimidinyl] methyl] -benzonitrile or its salt and, as a first excipient, sugar or sugar alcohol; and (2) the second part contains pioglitazone or a salt thereof and, as a second excipient, sugar or sugar alcohol. The invention relates to a solid formulation which comprises the following first and second parts: (1) ) -3-amino-1-piperidinyl] -3,4-dihydro-3-methyl-2,4-dioxo-1 (2H) -pyrimidinyl] methyl] -benzonitrile or its salt and, as a first excipient, sugar or sugar alcohol; and (2) the second part contains pioglitazone or a salt thereof and, as a second excipient, a sugar or sugar alcohol. |