http://rdf.ncbi.nlm.nih.gov/pubchem/patent/UA-90693-C2

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filingDate 2005-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac93c648b5afa9e4ecf71aa10b83c8d8
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publicationDate 2010-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber UA-90693-C2
titleOfInvention DERIVATIVES OF 2,4(4,6)-PYRIMIDINES$ DERIVATIVES OF 2,4(4,6)-PYRIMIDINES
abstract The invention relates to compounds of formula (I), their N-oxide forms, pharmaceutically acceptable additive salts and stereochemically isomeric forms, wherein Z and Z are NH; Y represents -Salkyl-, -Salkenyl-, -Salkyl-NR-Salkyl-, -Salkyl-NR-CO-Salkyl-, -Salkyl-CO-NH-, -Salkyl-NH-CO-, -Salkyl-CO- Net-CO-, -Salkyl-NH-CO-Het-, -Net-Salkyl-CO-NH- Salkyl, -Salkyl-NH-CO-L-NH-, -NH-CO-L-NH-, - Salkyl-CO-NH-L-CO-, -Salkyl-NH-CO-L-NH-CO-Salkyl, -Salkyl-CO-NH-L-CO-NH-Salkyl, -Salkyl-NR-CH- CO-NH-Salkyl-, Het-CO-Salkyl-, -Salkyl-CO-NH-Salkyl-CO-NH-, -Salkyl-NR-CO-Salkyl-NH-, -Salkyl-NH-CO-Net-CO - or -Salkyl-CO-Net-CO-NH-; X is a direct bond, O, -O-Salkyl-, -CO-Salkyl-, -NR-Salkyl-, -CO-NR-, Het-Salkyl- or Salkyl; X is a direct bond, O, -O-alkyl-, -CO-alkyl-, -NR-alkyl-, -CO-NR-, Het-C-alkyl- or alkyl; R and R, each independently, are hydrogen, halogen, Salkyloxy- or Salkyloxy-substituted Het or Salkyloxy-; R and R, each independently, are hydrogen or halogen; Represents hydrogen or cyano; R, R, R, R and R are hydrogen; Represents hydrogen or alkyl; R 1 and R 2 are hydrogen, Salkyl or Het-Salkyl-; L, or L each independently represent Salkyl, optionally substituted by one or, where possible, by two or more substituents selected from phenyl, methylsulfide, cyano, polyhalogenSalkylphenyl-, Salkyloxy, pyridinyl, mono- or di (Salkyl) amino or Cycloalkyl; Het, Het, Het, each independently, are morpholinyl, oxazolyl, isoxazolyl or piperazinyl; Het, Het, Het, each independently, are morpholinyl, piperazinyl, piperidinyl or pyrrolidinyl; Het is piperazinyl, piperidinyl, pyrrolidinyl or azetidinyl; Het is morpholinyl, oxazolyl, isoxazolyl or piperazinyl, wherein said Het is optionally substituted with alkyl; Het Het, everyone
priorityDate 2004-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 43.