| abstract |
The claimed invention relates to substituted bicyclo $ 3,1,0] heteroarylamides of formula I, where groups A, Q, X, Y, Z and R-R are defined in the description, which show activity as inhibitors of glycine transport, their pharmaceutically acceptable salts, pharmaceutical compositions containing they contain, and their use for improving cognitive ability and treating positive and negative symptoms of schizophrenia and other psychoses in mammals, including humans. X, Y, Z and R-R are defined in the description that act as inhibitors of glycine transport, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their use to improve cognitive ability and treat the positive and negative symptoms of schizophrenia and other psychoses in mammals, including humans. |