http://rdf.ncbi.nlm.nih.gov/pubchem/patent/UA-86094-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5305109c4efec4cbcdd8bc05bdb00399 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D489-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D489-00 |
| filingDate | 2005-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6078fdc168be625c1a3e33b6e35a8319 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d4905cae4861f4ce90af5a46dda9d363 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_daf383117f7c0a1bf62cedf2128bc870 |
| publicationDate | 2009-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | UA-86094-C2 |
| titleOfInvention | METHOD OF OBTAINING OXYCODONE $ METHOD OF OBTAINING OXYCODONE |
| abstract | A method of producing oxycodone of formula I by reacting thebaine of formula II or an analogue of formula III, where R is C-C1-6alkyl, alkylaryl, mainly benzyl, methoxybenzyl or allyl, with hydrogen peroxide or peroxo acid in the presence of oxalic acid mixed with acetic or formic acid. From the obtained crystalline precipitate of 4-hydroxycodeinone oxalate, by adding a base, 14-hydroxycodeinone of formula IV is liberated, which is hydrogenated with hydrogen in the presence of a catalyst, to obtain oxycodone of formula (I). Oxycodone is converted to hydrochloride, which is used as an active substance in analgesic formulations. |
| priorityDate | 2004-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.