abstract |
The invention relates to a group of hydronopol derivatives that are agonists of the human receptors ORL1 (nociceptin). The invention also relates to methods for producing these compounds, pharmaceutical compositions that contain a pharmacologically active amount of at least one of these new hydronopol derivatives as an active substance, and the use of these pharmaceutical compositions for the treatment of disorders associated with ORL1 receptors. The invention relates to compounds of general formula (1), where the radicals are niya, which are given in the description. |