http://rdf.ncbi.nlm.nih.gov/pubchem/patent/UA-81229-C2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a89514464d02d75ef2065a449fb0e617 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 |
filingDate | 2002-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2007-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | UA-81229-C2 |
titleOfInvention | Use of [6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1h-pyrrolizine-5-yl]-acetic acid in the treatment of articular cartilage or subchondral bone degeneration |
abstract | The invention relates to use [6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl]-acetic acid of the formula (la) a physiologically acceptable salt or aphysiologically hydrolysable ester thereof for the preparation of pharmaceutical composition for treatment or prevention of degeneration or destruction of articular cartilage and/or subchondral bone. A pharmaceutical composition, comprising: (A) [6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl]-acetic acid of the formula (la), a physiologically acceptable salt or a physiologically hydrolysable ester thereof; and (B) one or more members selected from the group consisting essentially of (1) polysulfatedglycosaminoglycan (PSGAG), glucosamine, chondroitin sulfate (CS), hyaluronic acid (HA), pentosan polysulfate (PPS), doxycycline, and minocycline. |
priorityDate | 2001-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.