http://rdf.ncbi.nlm.nih.gov/pubchem/patent/UA-81229-C2

Outgoing Links

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a89514464d02d75ef2065a449fb0e617
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40
filingDate 2002-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2007-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber UA-81229-C2
titleOfInvention Use of [6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1h-pyrrolizine-5-yl]-acetic acid in the treatment of articular cartilage or subchondral bone degeneration
abstract The invention relates to use [6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl]-acetic acid of the formula (la) a physiologically acceptable salt or aphysiologically hydrolysable ester thereof for the preparation of pharmaceutical composition for treatment or prevention of degeneration or destruction of articular cartilage and/or subchondral bone. A pharmaceutical composition, comprising: (A) [6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl]-acetic acid of the formula (la), a physiologically acceptable salt or a physiologically hydrolysable ester thereof; and (B) one or more members selected from the group consisting essentially of (1) polysulfatedglycosaminoglycan (PSGAG), glucosamine, chondroitin sulfate (CS), hyaluronic acid (HA), pentosan polysulfate (PPS), doxycycline, and minocycline.
priorityDate 2001-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 26.