abstract |
The subject of the invention is a method for the preparation of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthylamine derivatives or their salts. A compound of a certain formula is treated with an amine in the presence of an acid catalyst, for example, titanium tetrachloride, followed by reduction of the resulting intermediate compound with sodium borohydride and isolation of the target product in free form or in the form of a salt. |