http://rdf.ncbi.nlm.nih.gov/pubchem/patent/UA-61873-C2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9433d383d1922b3df0ca6c182c7d3925 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-00 |
| filingDate | 1996-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2003-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | UA-61873-C2 |
| titleOfInvention | Derivatives of 1-[2-(substituted vinyl)]-5h-2,3-benzodiazepine, a method for producing thereof (variants), intermediate compound, a pharmaceutical composition, a method for producing thereof and a method for treatment of central nervous system diseases |
| abstract | This invention relates to novel derivatives of 1-[2-(substituted vinyl)]-5H-2,3-benzodiazepine, a method for producing thereof , pharmaceutical composition, a method for producing the same and a method for treatment of central nervous system diseases. Compounds according to the invention have a general formula (I) , (I) wherein A and B together form a group of formula =C=N- or =CH-NH-; R1 represents phenyl which may contain between 2 and 3 hydroxyl groups or between 1 and 3 same or different substitutes selected of the group comprising halogen, trifluoromethyl, nitro-, cyano-, amino-, C1-3 alkylamino-, di-(C1-3 alkyl)amino-, C1-4 alkanoylamino-, C1-4 alkyl. C1-4 alkoxy-, carboxyl, (C1-4 alkoxy)carbonyl, C1-4 alkoxycarbonyloxy and methylenedioxyl, naphtyl, which may contain substituent , selected of the group comprising hydroxyl. C1-4 alkoxy- and C1-4 acyloxygroup, furyl, thienyl or indole; R2 represents hydrogen or C1-4 alkyl; R3 and R4 represents each C1-4 alkoxygroup, attached in thepositions 7 or 8 of benzodiazepine ring , or R3 and R4 together form 7,8- or 8,9-methylenedioxyl group, and have a considerable activity relative to the central nervous system. |
| priorityDate | 1995-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.