abstract |
The method of obtaining tablets is based on mixing the active substance with fillers, granulation and tableting. In order to improve the quality, granulation is carried out by spraying in a fluidized bed, mixing is carried out, mainly, chloropyramine [N - (n - chlorobenzyl) - N - (2 - pyridyl) - N '- N'-dimethylethylenediamine] with vinyl pyrrolidone-vinyl acetate and polyacrylic acid in in the presence of stearic acid and / or cetylstearic alcohol in isopropanol solution. |