| abstract |
This invention relates to enzyme inactivators which are used in medicine, mainly in cancer chemotherapy, especially in combination with antimetabolic antineoplastic agents such as 5-fluorouracil (5-FU). It is proposed to use 5-ethynyluracil for use in medicine, especially in cancer chemotherapy, together with a uracil reductase inactivator, for the production of medicinal preparations used in cancer chemotherapy, to protect against the toxicity of 5-fluorouracil, together with 5-fluorouracil or its precursor for treatment psoriasis, rheumatoid arthritis or human papillomavirus infection. |