| abstract |
The subject of the present invention is thiazolidinediones, a method for their preparation and drugs containing them. Thiazolidinediones of formula (I): in which A denotes a carbocyclic ring with 5 or 6 carbon atoms or a heterocyclic ring with 1 or 2 heteroatoms, the heteroatoms being oxygen, nitrogen or sulfur, and the heterocycles, if necessary, can be carried on one or more nitrogen atoms one oxygen atom, B - -CH = CH-, -N = CH-, -CH = N-, W - CH2, O, CH (OH) or CO, X - S, O or NR2, and the residue R2 is hydrogen , YN, R - naphthyl, pyridyl, furyl, thienyl or phenyl, optionally mono- or disubstituted with C1-Cs-alkyl, CF3, C1-C3-alkoxy, F, CI or bromine, R1 - hydrogen or C1-C6-alkyl , and n = 2, as well as their tautomers, enantiomers, diastereomers and physiologically acceptable salts. |