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filingDate 1994-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2001-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber UA-34481-C2
titleOfInvention DERIVATIVES OF 3 (2H) PYRIDAZINONE HAVING PHARMACEUTICAL ACTIVITY, BRONCHOLYTIC, ANTIALERGIC, ANTITHROMOCYTIC AGENTS ON THEIR PERSONS
abstract Derivative of 3 (2H) -pyridazinone of General formula (I) and its pharmaceutically acceptable salt, method for their preparation and pharmaceutical composition containing them as active ingredient: (I) where each of R1, R2 and R3, which are independent of each other from one - a hydrogen atom or an alkyl group C1-4, X - a chlorine atom or a bromine atom, Y1 - a hydrogen atom, a halogen atom, a nitro group, an amino group or an alkoxy group C1-4, Y2 - a hydrogen atom, a halogen atom, a hydroxyl group, alkyl group C1-4 or alkoxy group C1-4, A is an alkylene chain C1-5, which may be substituted by a hydroxyl group, B is a carbonyl group or methylene chain, which may be substituted by an alkyl group C1-4, and each of R4 And R5, which are independent of each other, is an alkyl group C1-4, or R4 is a hydrogen atom, and R5 is -Z-Ar (where Z is an alkylene chain C1-5, and Ar is an aromatic 6-membered ring that may contain one or two nitrogen atoms), or R4 and R5 together form a cyclic alkylene group C2-6, or R4 and R5 form together with an adjacent nitrogen atom 4-c substituted piperazine ring of formula: where R6 is an alkyl group C1-4
priorityDate 1993-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 36.