http://rdf.ncbi.nlm.nih.gov/pubchem/patent/UA-26400-C2
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_52c38b994e8b6584e1a077e50e3f0a6f |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D457-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D457-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 |
filingDate | 1993-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1999-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | UA-26400-C2 |
titleOfInvention | METHOD OF OBTAINING DERIVATIVE ERGOLICH |
abstract | The invention relates to a process for the preparation of an ergoline derivative of formula (l): wherein R1 represents an ethyl group, R2 represents a dimethylaminopropyl group (CH3) 2N (CH2) 3, R3 represents allyl, R4 and R5 represent a hydrogen atom. This substance is obtained by reacting an ergoline amide of formula (ll) with 1-4 equivalents of isocyanate of formula (lll): The reaction is carried out in a solvent such as dichloromethane, 1,1-dichloroethane or toluene, at a temperature of from 35 ° C to 60 ° C, in the presence of CuCl or CuCl2 and a phosphorus compound selected from PPh3, P (n-CIPh) 3, P (n-MePh) 3 and MePh2P. |
priorityDate | 1992-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.