http://rdf.ncbi.nlm.nih.gov/pubchem/patent/UA-140740-U
Outgoing Links
| Predicate | Object |
|---|---|
| filingDate | 2019-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | UA-140740-U |
| titleOfInvention | METHOD OF PLASTIC OF REAR WALL OF SPINAL CHANNEL IN RATS PERFORATED UNRESORPED POLYMER IMPLANT PRINTED ON 3D PRINTER PRINTER |
| abstract | The method of plasticity of the posterior wall of the spinal canal in rats perforated unsorbed polymer implant printed on a 3D printer filled with nanocomposite cermets, which is a method of surgical treatment, and after general anesthesia with a mixture of solutions of xylazine (calculation "Sedazin mg / Bio") kg of mass and ketamine ("Calypsol", Gideon Richter AO, Budapest, Hungary) at the rate of 70 mg / kg of body weight of the experimental animal intramuscularly remove the wool in the operating field and treatment of the operating field with antiseptic solutions, then spend dissection of the skin, subcutaneous tissue and aponeurosis on the posterior midline, the surgical wound is covered with sterile wipes and dissection of the aponeurosis, then skeletal processes and arches of the vertebrae of the required anatomical level (upper thoracic spine, segments of the lower below e segments of the lumbar plexus or lumbar spine, depending on the needs of the experiment), then with the help of pliers to remove the spinous processes and brackets of 2-3 vertebrae of an anatomical level, depending on the experimental group, then perform laminectomy at the level of 2-3 vertebrae , after which a wound dilator is applied to the wound to protect the spinal cord from drying out, as well as to facilitate laminectomy, the surface of the dura is regularly moistened with saline, after the selection of the spinal cord at 3 vertebrae, the lateral and anterior spinal cord for the anterior part of the spinal cord, then to simulate different terms of compression of the spinal cord perform lifting (traction) of the selected area of the spinal cord to stop the blood flow in its vessels and maintain in this state the required time (30, 45, 60 or 90 minutes depending on the experimental group ), p after holding the required time, traction is stopped, the spinal cord is returned to its previous place (depending on the period of compression, the restoration of blood flow in this area occurs differently, which further directly affects the postoperative neurological status of the animal, namely the level of neurological deficit in the lower extremities ), then carry out the reconstruction of the posterior wall of the spinal canal printed on a 3D printer perforated polymer implant made of bioresorbable plastic, filled with nanocomposite cermets, then the surgical wound is washed with antiseptic solutions and the muscles and aponeurosis impose surgical sutures, then wire skin and subcutaneous nodal sutures and final treatment of the sutured surgical wound with antiseptic solutions three times, in the postoperative period control behavioral reactions, neurological status of the animal, pathological neurological symptoms and the process of postoperative wound healing. |
| priorityDate | 2019-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 15.