http://rdf.ncbi.nlm.nih.gov/pubchem/patent/UA-136266-U
Outgoing Links
Predicate | Object |
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filingDate | 2019-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-08-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | UA-136266-U |
titleOfInvention | METHOD OF EVALUATION OF NEPHROTOXIC EFFECT OF ALUMINUM SALTS ON ION-REGULATORY FUNCTION OF KIDNEYS IN MATURE AND MATURE MATURE RATS |
abstract | A method for assessing the nephrotoxic effect of aluminum salts on the ion-regulating function of the kidneys in mature and immature rats by studying rats at night in low red light, which has little effect on the synthesis of melatonin of the pineal gland. The ion-regulating function of the kidneys is evaluated and the results are statistically processed. Studies of sexually mature 0.14-0.20 kg and immature 0.06-0.10 kg of nonlinear male white rats are performed separately. Aluminum chloride is administered at a dose of 200 mg / kg on a 1% starch suspension intragastrically daily for 14 days of the experiment at 8:00 o'clock. in the morning and at 20:00. P.m. Determine and evaluate the concentration of sodium ions in urine, mmol / l, excretion of sodium ions in urine, μmol / 2 h · 100 g, excretion of sodium ions, μmol / min · 100 g, clearance of sodium ion-free water, ml / 2 h · 100 g, clearance of sodium ions, ml / 2 h · 100 g and concentration index of sodium ions, um. from |
priorityDate | 2019-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 17.