http://rdf.ncbi.nlm.nih.gov/pubchem/patent/UA-118641-C2
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-02 |
filingDate | 2018-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | UA-118641-C2 |
titleOfInvention | METHOD OF DIAGNOSIS OF THE DEGREE OF ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH ESSENTIAL ARTERIAL HYPERTENSION COMBINED WITH 2 DIABETES TYPE 2 DIABETES |
abstract | The invention relates to a method for the diagnosis of type of endothelial dysfunction - ED in patients with arterial hypertension, including the determination of the concentration of endothelin-1 in blood plasma by enzyme-linked immunosorbent assay, in patients with essential arterial hypertension combined with type 2 diabetic additionally spectrophotometric method using the Griss reagent determine the sum of the concentrations of nitrites / nitrates by the formula NO2 + NO3 = NOx, then calculate the coefficient of endothelial dysfunction - KED by the formula KED = ET-1 / NOx, where ET-1 is the concentration of endothelin-1, fmol / ml; NOx is the sum of nitrite and nitrate concentrations, µmol / l, and if the KED value exceeds 0.28 and does not exceed 0.45 conventional units, the initial degree of endothelial dysfunction is diagnosed, with a value of 0.46 to 0.72 - a compensated degree of ED , at value (0.73 - decompensated degree of ED. |
priorityDate | 2018-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.