| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4b3fa9c30093d3d55bcedaff05a1d9ed |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0046
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4174 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 |
| filingDate |
2014-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c02290aaabb66efd907b802048abaea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d75a722be9a6a34e56107ad2bdec520
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60b558d62b1a3c5824c84aa911d2a5e0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d978a0722272386febd3eeb6739c1381 |
| publicationDate |
2018-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
UA-117544-C2 |
| titleOfInvention |
NACAL COMPOSITION WITH SEA WATER CONTENT AS AN EXCIPIENT THAT IMPROVES SUSTAINABILITY |
| abstract |
The present invention relates to a nasal composition with improved stability, its use and method of production. The nasal composition contains: xylometazoline hydrochloride (1), 0.01-0.1 wt./wt. % and ipratropium bromide (2), 0.01-0.1 wt./wt. %; and pharmaceutical excipients which are necessary for the preparation of dosage forms selected from the group comprising: nasal drops, liquid nasal sprays or nasal lavage fluids. Said nasal composition comprises purified seawater as a functional stability-enhancing excipient in amounts of 5-25 wt / wt. %. The nasal composition has an osmolality in the range of 270-820 mOsm / kg, a pH value in the range of 3-7, preferably in the range of 3-4.2 or 5.8-7.0 and most preferably in the range of 3.2-4.2, which demonstrates improved stability. |
| priorityDate |
2014-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |