http://rdf.ncbi.nlm.nih.gov/pubchem/patent/UA-112968-U
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
filingDate | 2016-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | UA-112968-U |
titleOfInvention | METHOD OF DETERMINATION OF OXIDATIVE STRESS IN AUXILIARY REPRODUCTIVE TECHNOLOGY PROGRAMS |
abstract | A method of determining oxidative stress in assisted reproductive technology programs, which includes evaluating the oxidative stress indicators of 8-isoprostane concentration in serum. Additionally reveal the degree of natural antioxidant protection of the body. The marker of 8-isoprostane concentration is chosen as a marker of oxidative stress. As a marker of natural antioxidant protection of the body - an indicator of the concentration of melatonin in the serum and in the follicular fluid. Determine the concentration of 8-isoprostane and melatonin in the serum at the initial stage of the study. If these rates exceed those in healthy people (norm), they declare the presence of oxidative stress and find it inappropriate to carry out controlled ovarian stimulation (CBS). If the values do not exceed the norms, conduct a CBS, then re-determine the indicators of 8-isoprostane and melatonin in the serum. If the serum 8-isoprostane values exceed the baseline, there is a high level of oxidative stress and a high likelihood of poor quality oocytes. Transvaginal puncture is then performed, 8-isoprostane and melatonin in the follicular fluid are determined and if these indicators exceed baseline, the probability of obtaining low quality oocytes is confirmed and embryo transfer is impractical. |
priorityDate | 2016-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 13.