abstract |
The invention relates to a pharmaceutical composition for the prevention and treatment of cardiovascular disease, which contains lercanidipine hydrochloride and valsartan as active components; and from 5 to 20% by weight of a super-disintegrating agent selected from the group consisting of croscarmellose, crospovidone and sodium starch glycolate and mixtures thereof, based on the total number of pharmaceutically acceptable excipients, where lercanidipine hydrochloride and valsartan are separately separated from each other after mixing separately prepared dried granules of lercanidipine hydrochloride and valsartan granules; and also to a method for preparing said composition. |