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filingDate 2010-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b83ff9b626d7eebb598f093e1971d27c
publicationDate 2014-12-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber UA-107369-C2
titleOfInvention DOSAGE FORM OF OBESITY ACTIVITY CONTAINING PREVIOUS MIXTURE WITH PURE ORLISTAT AND THE PREPARATION OF SUCH A COMPOSITION
abstract The invention relates to a dosage form with anti-obesity activity, which has a peripheral effect and contains a low-adhesive pre-mixture made of: orlistat in the form of a pure, unpelleted, active ingredient, where the content of orlistat in the previous mixture is less than 20% by weight; microcrystalline cellulose in an amount of about 37.5% (wt.) relative to the total weight of the previous mixture; lactose monohydrate in an amount of about 40.75% (wt.) relative to the total weight of the previous mixture; sodium lauryl sulfate in an amount of about 1.5% (wt.) relative to the total weight of the previous mixture; colloidal anhydrous silica in an amount of about 1.25% (wt.) relative to the total weight of the previous mixture; carboxymethyl starch in an amount of about 2.5% (wt.) relative to the total weight of the previous mixture; and sodium stearyl fumarate in an amount of about 1.5% relative to the total weight of the pre-mixture, where these components provide a pre-mixture of appropriate physical properties for easy preparation of oral dosage forms by including thickeners, flavors and odors and dyes.
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