| abstract |
The present invention describes novel pyrimidine and pyridine derivatives, their pharmaceutical compositions and the use of such compounds. For example, the pyrimidine and pyridine derivatives of the present invention can be used to treat, alleviate symptoms or prevent a condition that is sensitive to inhibition of anaplastic lymphoma (ALK) kinase activity, local adhesion kinase (FAK), zeta-linked protein kinase 70 (ZAP-70) ), insulin-like growth factor (IGF-1R), or combinations thereof. |